|
KMID : 0545120100200121677
|
|
Journal of Microbiology and Biotechnology
2010 Volume.20 No. 12 p.1677 ~ p.1680
|
|
|
The Effect of Protectants and pH Changes on the Cellular Growth and Succinic Acid Yield of Mannheimia succiniciproducens LPK7
|
|
Oh Young-Hoon
Oh In-Jae
Jung Chang-Kyou
Lee Sang-Yup
Lee Jin-Won
|
|
|
Abstract
|
|
|
|
The harmful effects of succinic acid and oxidative stress on cell growth were determined during batch fermentation with Mannheimia succiniciproducens LPK7, a powerful succinic acid-producing strain, and conditions were optimized to minimize these effects. In terms of toxicity, the cell concentration decreased as the concentration of succinic acid increased. By changing the pH from 6.5 to 7 during fermentation, the cell concentration increased by about 10%, and the level of succinic acid production was 6% higher than that of the control. In addition, by introducing protectants, the cell concentration increased by about 10%, and the level of succinic acid produced was increased by 3%.
|
|
|
KEYWORD
|
|
|
Mannheimia succiniciproducens LPK7, succinic acid, oxidative stress, cellular growth, protectants
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|